ZO Skin Health vs. Obagi Medical: Which Clinical Skincare Range is Right for You?

Both ZO Skin Health and Obagi Medical are renowned clinical skincare brands created by Dr. Zein Obagi, but they serve distinct purposes and skin concerns. While they share a science-backed foundation, understanding the differences can help you decide which range is right for your skin goals.

ZO Skin Health focuses on long-term skin health through controlled exfoliation, barrier repair, and active stimulation. Products like ZO Daily Power Defense and ZO Exfoliating Polish aim to rejuvenate skin from within, ideal for those ready to commit to a high-performance, medical-grade regimen. ZO’s protocols are often used under clinical supervision and are well-suited to those managing complex skin concerns like severe acne, pigmentation, and textural damage.

Obagi Medical, similarly, offers highly effective solutions for aging, sun damage, and dull skin. Hero products such as Obagi Professional-C Serum (available in 3 strengths), Obagi ELASTIderm Facial Serum, and Obagi Hydro-Drops target specific concerns with precision and fewer transitional effects. The formulas tend to be gentler, making them a go-to for daily maintenance and prevention without a full skin reset.

Both lines are results-driven, but the choice often comes down to your skin’s tolerance, your aesthetic goals, and how much active change you're ready for.

Not sure which brand aligns with your skin's needs? Book a 1:1 virtual consultation with our resident clinician, Dr. Mandy for expert, personalised guidance tailored to your goals and skin condition.